Cardiopulmonary Responses and Prognosis in Hypertrophic Cardiomyopathy

This study sought to discover the key determinants of exercise capacity, maximal oxygen consumption (oxygen uptake [Vo2]), and ventilatory efficiency (ventilation/carbon dioxide output [VE/Vco2] slope) and assess the prognostic potential of metabolic exercise testing in hypertrophic cardiomyopathy (HCM). The intrinsic mechanisms leading to reduced functional tolerance in HCM are unclear. The study sample included 156 HCM patients consecutively...