<p>Epigenetic mechanism controls <em>PDK4</em> gene activation before and after exercise therapy following artificial knee arthroplasty</p>
Abstract
DNA methylation is thought to play a role in exercise-induced gene expression. We aimed to examine changes in muscular strength and body composition in elderly patients with end-stage knee osteoarthritis before and after artificial knee arthroplasty and exercise therapy. We aimed to confirm the relationship between DNA methylation and body composition, using the methylation rate of the pyruvate dehydrogenase kinase 4 (PDK4) gene that regulates...
Paper Details
Title
<p>Epigenetic mechanism controls <em>PDK4</em> gene activation before and after exercise therapy following artificial knee arthroplasty</p>
Published Date
Aug 1, 2019
Volume
Volume 14
Pages
1433 - 1443
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