Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages

Volume: 54, Issue: 4, Pages: 1802244 - 1802244
Published: Jul 18, 2019
Abstract
Increased reactive oxygen species (ROS) have been implicated in the pathophysiology of chronic obstructive pulmonary disease (COPD). This study examined the effect of exogenous and endogenous oxidative stress on macrophage phagocytosis in patients with COPD. Monocyte-derived macrophages (MDMs) were generated from non-smoker, smoker and COPD subjects, differentiated in either granulocyte macrophage-colony stimulating factor (G-Mφ) or...
Paper Details
Title
Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages
Published Date
Jul 18, 2019
Volume
54
Issue
4
Pages
1802244 - 1802244
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