Clinical importance of Bcl-2-like 11 deletion polymorphism in idiopathic pulmonary fibrosis
Abstract
Reactive oxygen species (ROS) can play a role in the pathogenesis of Idiopathic Pulmonary Fibrosis (IPF) by contributing to epithelial damage. Bcl-2-like 11 (BIM) is involved in the generation of ROS via forkhead box O3 (FOXO3), and a BIM deletion polymorphism related to apoptosis has been reported to be specific to Asians. Here we examine the clinical features of IPF in patients with BIM deletion polymorphism.In this single-center retrospective...
Paper Details
Title
Clinical importance of Bcl-2-like 11 deletion polymorphism in idiopathic pulmonary fibrosis
Published Date
Jul 1, 2019
Journal
Volume
11
Issue
7
Pages
2981 - 2989
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