Original paper

Enzyme-powered Janus nanomotors launched from intratumoral depots to address drug delivery barriers

Volume: 375, Pages: 122109 - 122109
Published: Nov 1, 2019
Abstract
The delivery of nanoparticles encounters a series of biological barriers from systemic clearance, tumor accumulation, cellular uptake and intracellular drug release. In this study we propose enzyme-powered nanomotors launched from intratumorally injected local depots to overcome these delivery barriers. Hydroxyapatite-embedded mesoporous silica nanoparticles ([email protected]) are prepared by formation of silica layers on CaCO3 nanoparticles,...
Paper Details
Title
Enzyme-powered Janus nanomotors launched from intratumoral depots to address drug delivery barriers
Published Date
Nov 1, 2019
Volume
375
Pages
122109 - 122109
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