Abstract 3584: Role of long noncoding RNA LINC00461 in EGFR-TKIs resistant non-small cell lung cancer

Chemo-resistance is one of the major factors limiting the therapeutic efficacy and prognosis of non-small cell lung cancer (NSCLC) patients, especially with patients who harbor epidermal growth factor receptor (EGFR)-activating mutations. Accumulating evidence suggests that aberrant expression of long noncoding RNAs (lncRNAs) is in part associated with carcinogenesis. Therefore, we tried to identify lncRNAs and their potential target genes in...