Synthesis and anti-cancer activities of glycosides and glycoconjugates of diterpenoid isosteviol
Abstract
A series of glycosides and glycoconjugates of diterpenoid isosteviol (16-oxo-ent-beyeran-19-oic acid) with various monosaccharide residues were synthesized and their cytotoxicity against some human cancer and normal cell lines was assayed. Most of the synthesized compounds demonstrated moderate to significant cytotoxicity against human cancer cell lines M-HeLa and MCF-7. Three lead compounds exhibited selective cytotoxic activities against...
Paper Details
Title
Synthesis and anti-cancer activities of glycosides and glycoconjugates of diterpenoid isosteviol
Published Date
Jan 1, 2019
Journal
Volume
10
Issue
8
Pages
1488 - 1498
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