In vitro and in vivo efficacy of anti‐chikungunya virus monoclonal antibodies produced in wild‐type and glycoengineered Nicotiana benthamiana plants

Summary Chikungunya virus ( CHIKV ) is a mosquito‐transmitted alphavirus, and its infection can cause long‐term debilitating arthritis in humans. Currently, there are no licensed vaccines or therapeutics for human use to combat CHIKV infections. In this study, we explored the feasibility of using an anti‐ CHIKV monoclonal antibody ( mA b) produced in wild‐type ( WT ) and glycoengineered (∆ XFT ) Nicotiana benthamiana plants in treating CHIKV...