Original paper
Enzymatic reconstruction of glycosaminoglycan oligosaccharides
Abstract
The transglycosylation mechanism of testicular hyaluronidase, which is an endo-β-N-acetylhexosaminidase, was investigated with the aim of performing enzymatic synthesis of glycosaminoglycan (GAG) sugar chains. It was found that disaccharide units (glucuronic acid β1-3-N-accetylglucosamine β1-4) are successively released from the nonreducing terminal of a donor hyaluronic acid (HA) and rapidly transferred to the glucuronic acid residue at the...
Paper Details
Title
Enzymatic reconstruction of glycosaminoglycan oligosaccharides
Published Date
Dec 1, 2001
Volume
1223
Pages
239 - 244
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Notes
History