Original paper
New Paradigms for eIF4E in Translating the Genome of Normal and Cancer Cells
Published: Jan 1, 2014
Abstract
Author(s): Truitt, Morgan Lee | Advisor(s): Ruggero, Davide | Abstract: Although it was first observed nearly a century ago that transformed cells are marked by enlarged nucleoli, where ribosomal RNA synthesis and ribosome assembly occur, it has only recently become clear that deregulated protein synthesis plays a causal role in the development and progression of cancer. Indeed, aberrant mRNA translation has emerged as a hallmark of oncogenic...
Paper Details
Title
New Paradigms for eIF4E in Translating the Genome of Normal and Cancer Cells
Published Date
Jan 1, 2014
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Notes
History