Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B
Abstract
Enterovirus B (EV-B), a major proportion of the genus Enterovirus in the family Picornaviridae, is the causative agent of severe human infectious diseases. Although cellular receptors for coxsackievirus B in EV-B have been identified, receptors mediating virus entry, especially the uncoating process of echovirus and other EV-B remain obscure. Here, we found that human neonatal Fc receptor (FcRn) is the uncoating receptor for major EV-B. FcRn...
Paper Details
Title
Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B
Published Date
May 1, 2019
Journal
Volume
177
Issue
6
Pages
1553 - 1565.e16
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