Original paper

Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders

Volume: 24, Issue: 9, Pages: 1248 - 1257
Published: May 14, 2019
Abstract
In 2003 Rubenstein and Merzenich hypothesized that some forms of Autism (ASD) might be caused by a reduction in signal-to-noise in key neural circuits, which could be the result of changes in excitatory-inhibitory (E-I) balance. Here, we have clarified the concept of E-I balance, and updated the original hypothesis in light of the field's increasingly sophisticated understanding of neuronal circuits. We discuss how specific developmental...
Paper Details
Title
Excitation-inhibition balance as a framework for investigating mechanisms in neuropsychiatric disorders
Published Date
May 14, 2019
Volume
24
Issue
9
Pages
1248 - 1257
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.