Muscle-like fatigue-resistant hydrogels by mechanical training

Skeletal muscles possess the combinational properties of high fatigue resistance (1,000 J/m2), high strength (1 MPa), low Young's modulus (100 kPa), and high water content (70 to 80 wt %), which have not been achieved in synthetic hydrogels. The muscle-like properties are highly desirable for hydrogels' nascent applications in load-bearing artificial tissues and soft devices. Here, we propose a strategy of mechanical training to achieve the...