LC3-associated phagocytosis - The highway to hell for phagocytosed microbes
Abstract
Phagocytes ingest, kill and degrade invading microbes in a process called phagocytosis. LC3-associated phagocytosis (LAP) combines the molecular machinery of phagocytosis with that of autophagy, the cellular pathway for ingestion of cytoplasmic components, resulting in the eponymous association of ‘microtubule-associated proteins 1 A/1B light chain 3’ (LC3) with the phagosomal membrane. The LC3-decorated phagosomes, or LAPosomes, show enhanced...
Paper Details
Title
LC3-associated phagocytosis - The highway to hell for phagocytosed microbes
Published Date
May 1, 2020
Volume
101
Pages
68 - 76
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