Diagnostic Accuracy of Conventional Cell Blocks Along with p16INK4 and Ki67 Biomarkers as Triage Tests in Resource-poor Organized Cervical Cancer Screening Programs

Background: Liquid based cytology with dual biomarkers has improved sensitivity and specificity in detectinghigh grade cervical intraepithelial neoplasia (CIN). In low resource settings, especially in organized camps, LBC iscostly and immunohistochemistry on conventional pap smears is difficult to standardize with consumption of lots ofreagents. In present study, to improve the accuracy of conventional pap smears and reduce the cost of...