Original paper
GnRH Pulse Generator Activity Across the Estrous Cycle of Female Mice
Abstract
A subpopulation of kisspeptin neurons located in the arcuate nucleus (ARN) operate as the GnRH pulse generator. The activity of this population of neurons can be monitored in real-time for long periods using kisspeptin neuron-selective GCaMP6 fiber photometry. Using this approach, we find that ARN kisspeptin neurons exhibit brief (∼50 seconds) periods of synchronized activity that precede pulses of LH in intact female mice. The dynamics and...
Paper Details
Title
GnRH Pulse Generator Activity Across the Estrous Cycle of Female Mice
Published Date
Apr 24, 2019
Volume
160
Issue
6
Pages
1480 - 1491
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Notes
History