Spatially varying age–period–cohort analysis with application to US mortality, 2002–2016

Many public health databases index disease counts by age groups and calendar periods within geographic regions (e.g., states, districts, or counties). Issues around relative risk estimation in small areas are well-studied; however, estimating trend parameters that vary across geographic regions has received less attention. Additionally, small counts (e.g., <10 in most publicly accessible databases are censored, further complicating...