Review paper
Treatment of Organophosphate Poisoning with Experimental Oximes: A Review
Abstract
Standard therapy of Organophosphorus Compound (OPC) poisoning with oxime-type acetylcholinesterase (AChE) reactivators is unsatisfactory. New bispyridinium oximes have therefore been synthesized. This review summarizes in vitro characteristics of established (pralidoxime, obidoxime, trimedoxime, HI-6) and experimental (K-)oximes, and compares their protective efficacy in vivo, when administered shortly after exposure to...
Paper Details
Title
Treatment of Organophosphate Poisoning with Experimental Oximes: A Review
Published Date
Jul 1, 2019
Journal
Volume
23
Issue
5
Pages
628 - 639
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