ILC3 function as a double-edged sword in inflammatory bowel diseases
Abstract
Inflammatory bowel diseases (IBD), composed mainly of Crohn's disease (CD) and ulcerative colitis (UC), are strongly implicated in the development of intestinal inflammation lesions. Its exact etiology and pathogenesis are still undetermined. Recently accumulating evidence supports that group 3 innate lymphoid cells (ILC3) are responsible for gastrointestinal mucosal homeostasis through moderate generation of IL-22, IL-17, and GM-CSF in the...
Paper Details
Title
ILC3 function as a double-edged sword in inflammatory bowel diseases
Published Date
Apr 8, 2019
Journal
Volume
10
Issue
4
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