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doi.org/10.1016/j.phymed.2019.152907

Cycloastragenol can negate constitutive STAT3 activation and promote paclitaxel-induced apoptosis in human gastric cancer cells

..., Kwang Seok Ahn
55
Phytomedicine7.90
Volume: 59, Pages: 152907 - 152907
Published: Jun 1, 2019
Abstract
Cycloastragenol (CAG), a triterpene aglycone is commonly prescribed for treating hypertension, cardiovascular disease, diabetic nephropathy, viral hepatitis, and various inflammatory-linked diseases.We investigated CAG for its action on signal transducer and activator of transcription 3 (STAT3) activation cascades, and its potential to sensitize gastric cancer cells to paclitaxel-induced apoptosis.The effect of CAG on STAT3 phosphorylation and...
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Paper Details
Title
Cycloastragenol can negate constitutive STAT3 activation and promote paclitaxel-induced apoptosis in human gastric cancer cells
DOI
doi.org/10.1016/j.phymed.2019.152907
Published Date
Jun 1, 2019
Journal
Phytomedicine
Volume
59
Pages
152907 - 152907
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