Ivabradine

Cardiology

Heart rate

Anesthesia

Blood pressure

Internal medicine

Heart disease

Medicine

Antiarrhythmic agent

HeartRhythm Case Reports

Key Teaching Points•Ivabradine is a novel heart rate–reducing agent that acts via selective inhibition of the pacemaker current.•Ivabradine demonstrates use dependence, resulting in a greater effect at higher heart rates.•Ivabradine has a hemodynamically neutral profile, in contrast to many alternative antiarrhythmic agents.•Ivabradine shows promise as an effective treatment for automatic tachyarrhythmias in pediatric and congenital heart disease patients. •Ivabradine is a novel heart rate–reducing agent that acts via selective inhibition of the pacemaker current.•Ivabradine demonstrates use dependence, resulting in a greater effect at higher heart rates.•Ivabradine has a hemodynamically neutral profile, in contrast to many alternative antiarrhythmic agents.•Ivabradine shows promise as an effective treatment for automatic tachyarrhythmias in pediatric and congenital heart disease patients.

Ivabradine for treatment of tachyarrhythmias in children and young adults