miR‐31 shuttled by halofuginone‐induced exosomes suppresses MFC‐7 cell proliferation by modulating the HDAC2/cell cycle signaling axis

Volume: 234, Issue: 10, Pages: 18970 - 18984
Published: Mar 27, 2019
Abstract
Traditional Chinese medicine (TCM) are both historically important therapeutic agents and important source of new drugs. Halofuginone (HF), a small molecule alkaloid derived from febrifugine, has been shown to exert strong antiproliferative effects that differ markedly among various cell lines. However, whether HF inhibits MCF‐7 cell growth in vitro and underlying mechanisms of this process are not yet clear. Here, we offer the strong evidence...
Paper Details
Title
miR‐31 shuttled by halofuginone‐induced exosomes suppresses MFC‐7 cell proliferation by modulating the HDAC2/cell cycle signaling axis
Published Date
Mar 27, 2019
Volume
234
Issue
10
Pages
18970 - 18984
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