A Synaptic Perspective of Fragile X Syndrome and Autism Spectrum Disorders.
Abstract
Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS), autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are therefore classified as synaptopathies. FXS and ASDs, while clinically and genetically distinct, share significant comorbidity, suggesting that there may be a common molecular and/or cellular basis, presumably at the synapse. In this article, we review brain architecture...
Paper Details
Title
A Synaptic Perspective of Fragile X Syndrome and Autism Spectrum Disorders.
Published Date
Mar 20, 2019
Journal
Volume
101
Issue
6
Pages
1070 - 1088
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