Internal medicine

Biology

Animal science

Oreochromis

Aflatoxin

Fishery

Calcium

Fish <Actinopterygii>

Food science

Medicine

Zagazig Veterinary Journal/Zagazig Veterinary Journal (Online)

Different ways have been used in an attempt to decrease the risk of aflatoxicosis in fish.This study was undertaken to compare the possible alleviative effects of hydrated sodium calcium aluminosilicate (HSCAS) and Saccharomyces cerevisiae against the toxic impact of aflatoxin B 1 (AFB 1 ) on Oreochromis niloticus (O.niloticus).Therefore, 180 normal cultured monosex O. niloticus were randomly allocated into 6 equal groups.Group 1, was received the basal ration only.Group 2, was fed a basal ration supplemented with 0.5% HASCAS.Group 3, was fed a basal diet enriched with 0.25% Saccharomyces cerevisiae.Group 4, was received a diet intoxicated with 2.5 ppm aflatoxin B 1 .Group 5, was fed a diet intoxicated with 2.5 ppm AFB 1 with 0.5% HSCAS.Group 6, was fed a diet intoxicated with 2.5 ppm AFB 1 with 0.25% S. cerevisae.AFB 1 intoxication induced mortality 16.67 %, leucopenia, lymphopenia, neutrophilia with a significant decrease in phagocytic % and index.Furthermore, significant increases in serum creatinine, ALT and ALP as well as a significant decrease in total protein, albumin and globulin were recorded.Moreover, accumulation of aflatoxin residues in O. niloticus flesh (5 ppb) and liver (15 ppb).While, supplementation of AFB 1 intoxicated diet either with S. cerevisiae or HSCAS ameliorated the drastic effects of aflatoxin on O. niloticus and S. cerevisiae appear to be more effective in the protection of fish from aflatoxicosis than HSCAS.

Comparative ameliorative effect of Hydrated sodium calcium aluminosilicate and Saccharomyces cerevisiae (Brewer's yeast) against toxic impact of aflatoxin B1 in Oreochromis niloticus (Nile tilapia)