Review paper
CRISPR-Cas in Streptococcus pyogenes
Abstract
The discovery and characterization of the prokaryotic CRISPR-Cas immune system has led to a revolution in genome editing and engineering technologies. Despite the fact that most applications emerged after the discovery of the type II-A CRISPR-Cas9 system of Streptococcus pyogenes, its biological importance in this organism has received little attention. Here, we provide a comprehensive overview of the current knowledge about CRISPR-Cas systems...
Paper Details
Title
CRISPR-Cas in Streptococcus pyogenes
Published Date
Mar 11, 2019
Journal
Volume
16
Issue
4
Pages
380 - 389