Internal medicine

Pathology

Sociology

Pediatrics

Cohort study

Population

Biology

Offspring

World Wide Web

Demography

Sampling frame

Index (typography)

Longitudinal study

Pregnancy

Computer science

Cohort

Gerontology

Genetics

Medicine

Environmental health

Wellcome Open Research

<ns4:p>The Avon Longitudinal Study of Parents and Children (ALSPAC) is a prospective population-based study. Initial recruitment of pregnant women took place in 1990-1992 and the health and development of the index children from these pregnancies and their family members have been followed ever since. The eligible sampling frame was constructed retrospectively using linked recruitment and health service records. Additional offspring that were eligible to enrol in the study have been welcomed through major recruitment drives at the ages of 7 and 18 years; and through opportunistic contacts since the age of 7. This data note provides a status update on the recruitment of the index children since the age of 7 years with a focus on enrolment since the age of 18, which has not been previously described. A total of 913 additional G1 (the cohort of index children) participants have been enrolled in the study since the age of 7 years with 195 of these joining since the age of 18. This additional enrolment provides a baseline sample of 14,901 G1 participants who were alive at 1 year of age.</ns4:p>

The Avon Longitudinal Study of Parents and Children (ALSPAC): an update on the enrolled sample of index children in 2019