Characterization of chemical constituents and identification of absorbed components and metabolites in rat plasma of Fu‐Ke‐Zai‐Zao pills by ultra high performance liquid chromatography with quadrupole time‐of‐flight mass spectrometry

Fu‐Ke‐Zai‐Zao pills, the famous traditional Chinese medicine formula, composed of 42 medicinal herbs, have been widely used to treat various gynecological diseases. However, the chemical constituents and metabolic profiling of Fu‐Ke‐Zai‐Zao pills remain largely unknown, which hampers improvement of the quality control and pharmacological elucidation of this formula. In the present study, a sensitive and selective ultra high performance liquid...