Original paper
Loss of intestinal sympathetic innervation elicits an innate immune driven colitis
Abstract
Both the parasympathetic and sympathetic nervous system exert control over innate immune responses. In inflammatory bowel disease, sympathetic innervation in intestinal mucosa is reduced. Our aim was to investigate the role of sympathetic innervation to the intestine on regulation of the innate immune responses.In lipopolysaccharide (LPS)-stimulated macrophages, we evaluated the effect of adrenergic receptor activation on cytokine production and...
Paper Details
Title
Loss of intestinal sympathetic innervation elicits an innate immune driven colitis
Published Date
Jan 7, 2019
Journal
Volume
25
Issue
1
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Notes
History