Review paper
Involvement of CXCR4 in Normal and Abnormal Development
Abstract
CXC motif chemokine receptor type 4 (CXCR4) is associated with normal and abnormal development, including oncogenesis. The ligand of CXCR4 is stromal cell-derived factor (SDF), also known as CXC motif ligand (CXCL) 12. Through the SDF-1/CXCR4 axis, both homing and migration of hematopoietic (stem) cells are regulated through niches in the bone marrow. Outside of the bone marrow, however, SDF-1 can recruit CXCR4-positive cells from the bone...
Paper Details
Title
Involvement of CXCR4 in Normal and Abnormal Development
Published Date
Feb 20, 2019
Journal
Volume
8
Issue
2
Pages
185 - 185
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Notes
History