Original paper
Antitumor effect of XCT790, an ERRα inverse agonist, on ERα-negative endometrial cancer cells
Abstract
The estrogen-related receptor (ERR) α is structurally similar to classical estrogen receptors (ERs), but is considered to be an orphan nuclear receptor. We previously found that ERRα regulates uterine endometrial cancer progression. Here, we investigated the efficacy of XCT790, a selective inverse agonist of ERRα, on endometrial cancer cells in vitro and in vivo. HEC-1A and KLE, ERα-negative endometrial cancer cells exhibiting high ERRα...
Paper Details
Title
Antitumor effect of XCT790, an ERRα inverse agonist, on ERα-negative endometrial cancer cells
Published Date
Jan 31, 2019
Journal
Volume
42
Issue
2
Pages
223 - 235
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Notes
History