Original paper
The Neonatal and Adult Human Testis Defined at the Single-Cell Level
Abstract
Spermatogenesis has been intensely studied in rodents but remains poorly understood in humans. Here, we used single-cell RNA sequencing to analyze human testes. Clustering analysis of neonatal testes reveals several cell subsets, including cell populations with characteristics of primordial germ cells (PGCs) and spermatogonial stem cells (SSCs). In adult testes, we identify four undifferentiated spermatogonia (SPG) clusters, each of which...
Paper Details
Title
The Neonatal and Adult Human Testis Defined at the Single-Cell Level
Published Date
Feb 1, 2019
Journal
Volume
26
Issue
6
Pages
1501 - 1517.e4
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Notes
History