Critical Excipient Attributes Relevant to Solid Dosage Formulation Manufacturing

The objective of this article is to review the critical material attributes of pharmaceutical excipients employed in solid dosage manufacturing and link them to critical quality attributes (CQAs). Material attributes can have a profound impact on CQAs of product. The importance of particle size, particle morphology, density, moisture content, and polymorphism to product CQAs is discussed. Physical functional attributes of excipients are...