Review paper
Multivalency in Drug Delivery–When Is It Too Much of a Good Thing?
Abstract
Multivalency plays a large role in many biological and synthetic systems. The past 20 years of research have seen an explosion in the study of multivalent drug delivery systems based on scaffolds such as dendrimers, polymers, and other nanoparticles. The results from these studies suggest that when it comes to the number of ligands, sometimes, to quote Shakespeare, "too much of a good thing" is an apt description. Recent theoretical studies on...
Paper Details
Title
Multivalency in Drug Delivery–When Is It Too Much of a Good Thing?
Published Date
Feb 11, 2019
Journal
Volume
30
Issue
3
Pages
503 - 514