Chromatin accessibility and the regulatory epigenome
Abstract
Physical access to DNA is a highly dynamic property of chromatin that plays an essential role in establishing and maintaining cellular identity. The organization of accessible chromatin across the genome reflects a network of permissible physical interactions through which enhancers, promoters, insulators and chromatin-binding factors cooperatively regulate gene expression. This landscape of accessibility changes dynamically in response to both...
Paper Details
Title
Chromatin accessibility and the regulatory epigenome
Published Date
Jan 23, 2019
Journal
Volume
20
Issue
4
Pages
207 - 220
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Notes
History