Bioassay

Rhizome

Glycoside

Stereochemistry

Biology

Circular dichroism

Chemistry

In vitro

Absolute configuration

HeLa

Botany

Genetics

Biochemistry

Traditional medicine

Medicine

Natural Product Research

Six sesquiterpenoids and four lignans (1-10) were isolated from the n-BuOH extract of the rhizomes of Atractylodes lancea. Among them, the new sesquiterpenoid glycoside named (4 R, 5S, 7R)-hinesolone-11-O-β-ᴅ-glucopyranoside (1), along with three known compounds (2-4) were first obtained from this genus. All the isolates were elucidated by spectroscopic analyses and chemical methods, and the absolute configurations were assigned by electronic circular dichroism spectroscopy technique. In addition, the cytotoxic bioassay of compound 1 was evaluated and results showed it had no significant antitumor activity against human cancer cell lines MCF-7, HepG-2 and Hela.

New sesquiterpenoid glycoside from the rhizomes of <i>Atractylodes lancea</i>

New sesquiterpenoid glycoside from the rhizomes of Atractylodes lancea