43. TCP approach to predict the pathological response based on MRI-based quantification of early tumor regression in rectal cancer neo-adjuvant radio-chemotherapy

Purpose Predictive models based on tumor regression represent a promising field of investigation in neo-adjuvant radio-chemotherapy (RCT) of rectal cancer (Rca). The aim of this study was to introduce a radiobiological index based on early tumor regression and to test its ability in predicting the tumor pathological response (pR). Methods Seventy-four patients were treated in the period 2009–2016 with Helical Tomotherapy (HT) following an...