Graphene serves as the most disruptive material in the twenty-first century and plays an unsubstitutable role in solving the sustainable development problems of energy crises, water shortages, and environmental pollution. Recently, obtaining a sustainable competitive advantage (SCA) in the field of graphene has gained increasing attention from both researchers and practitioners. However, few attempts have been made to summarize the SCA of this field by applying patent information. Basing on a patent-based multi-level perspective (MLP), this study aims to develop an approach to identify SCA in the target technological area by conducting a patent review from the comprehensive perspectives of the macro landscape, meso socio-technical system, and micro niches, and then integrate patent analysis with technology life cycle (TLC) theory to examine patents involving global technological competition. The effectiveness of the approach is verified with a case study on graphene. The results show that the graphene field is an emerging and fast-growing technological field, with an increasing number of patents over the year. The TLC of graphene technology demonstrated an approximate S shape, with China, the U.S., Korea, and Japan filing the largest number of graphene patents. Evidenced by Derwent Manual Codes, we found an increase in consideration given to technological application and material preparation topics over time, and research hotspots and fronts that have SCA. In terms of a leading country or region with SCA, the U.S., with a high foreign patent filing rate, large number of high forward citation patents, strong assignees’ competitive position, and large number of high-strength patents, was still the most powerful leader, with a higher SCA in the graphene industry. Korea also obtained a relatively higher SCA and will be a promising competitor in this field. Although China was shown to be catching-up very rapidly in the total number of graphene patents, the apparent innovation gaps in the foreign patent filing rate, hi...