Review paper

Immune checkpoint inhibitors: recent progress and potential biomarkers

Volume: 50, Issue: 12, Pages: 1 - 11
Published: Dec 1, 2018
Abstract
Cancer growth and progression are associated with immune suppression. Cancer cells have the ability to activate different immune checkpoint pathways that harbor immunosuppressive functions. Monoclonal antibodies that target immune checkpoints provided an immense breakthrough in cancer therapeutics. Among the immune checkpoint inhibitors, PD-1/PD-L1 and CTLA-4 inhibitors showed promising therapeutic outcomes, and some have been approved for...
Paper Details
Title
Immune checkpoint inhibitors: recent progress and potential biomarkers
Published Date
Dec 1, 2018
Volume
50
Issue
12
Pages
1 - 11
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