Molecular Mechanisms of Early and Late LTP

Volume: 44, Issue: 2, Pages: 281 - 296
Published: Feb 1, 2019
Abstract
LTP is the most intensively studied cellular model of the memory and generally divided at least two distinct phases as early and late. E-LTP requires activation of CaMKII that initiates biochemical events and trafficking of proteins, which eventually potentiate synaptic transmission, and is independent of de novo protein synthesis. In contrast, L-LTP requires gene expression and local protein synthesis regulated via TrkB receptor- and functional...
Paper Details
Title
Molecular Mechanisms of Early and Late LTP
Published Date
Feb 1, 2019
Volume
44
Issue
2
Pages
281 - 296
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