Original paper
Glucagon attenuates lipid accumulation in cow hepatocytes through AMPK signaling pathway activation
Abstract
The ketotic cows displayed hepatic lipid metabolic disorder and high blood concentration of glucagon. Importantly, adenosine monophosphate‐activated protein kinase (AMPK) signaling pathway plays an important role in the hepatic lipid homeostasis. Therefore, the aim of this study was to investigate the effect of glucagon on AMPK pathway and its underlying mechanism on lipid metabolism in cow hepatocytes. Cow hepatocytes were cultured and treated...
Paper Details
Title
Glucagon attenuates lipid accumulation in cow hepatocytes through AMPK signaling pathway activation
Published Date
Nov 27, 2018
Volume
234
Issue
5
Pages
6054 - 6066