A Systems-Level Study Reveals Regulators of Membrane-less Organelles in Human Cells
Abstract
Membrane-less organelles (MLOs) are liquid-like subcellular compartments that form through phase separation of proteins and RNA. While their biophysical properties are increasingly understood, their regulation and the consequences of perturbed MLO states for cell physiology are less clear. To study the regulatory networks, we targeted 1,354 human genes and screened for morphological changes of nucleoli, Cajal bodies, splicing speckles, PML...
Paper Details
Title
A Systems-Level Study Reveals Regulators of Membrane-less Organelles in Human Cells
Published Date
Dec 1, 2018
Journal
Volume
72
Issue
6
Pages
1035 - 1049.e5
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History