Review paper
The calcium-sensing receptor in physiology and in calcitropic and noncalcitropic diseases
Abstract
The Ca2+-sensing receptor (CaSR) is a dimeric family C G protein-coupled receptor that is expressed in calcitropic tissues such as the parathyroid glands and the kidneys and signals via G proteins and β-arrestin. The CaSR has a pivotal role in bone and mineral metabolism, as it regulates parathyroid hormone secretion, urinary Ca2+ excretion, skeletal development and lactation. The importance of the CaSR for these calcitropic processes is...
Paper Details
Title
The calcium-sensing receptor in physiology and in calcitropic and noncalcitropic diseases
Published Date
Nov 15, 2018
Journal
Volume
15
Issue
1
Pages
33 - 51