Original paper
Protocadherin-1 is essential for cell entry by New World hantaviruses
Abstract
The zoonotic transmission of hantaviruses from their rodent hosts to humans in North and South America is associated with a severe and frequently fatal respiratory disease, hantavirus pulmonary syndrome (HPS)1,2. No specific antiviral treatments for HPS are available, and no molecular determinants of in vivo susceptibility to hantavirus infection and HPS are known. Here we identify the human asthma-associated gene protocadherin-1 (PCDH1)3–6 as...
Paper Details
Title
Protocadherin-1 is essential for cell entry by New World hantaviruses
Published Date
Nov 1, 2018
Journal
Volume
563
Issue
7732
Pages
559 - 563
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Notes
History