Government (linguistics)

Economic growth

Family medicine

Bioinformatics

Grey literature

Biology

The Internet

World Wide Web

Philosophy

Political science

Multinational corporation

Economics

Legislation

MEDLINE

Public relations

Computer science

Linguistics

Medicine

Orphan drug

Developing country

Intractable & Rare Diseases Research

Previous studies have focused on the comparison of specific laws among multiple countries and regions; for example, laws related to facilitating treatments with orphan drugs or laws seeking to address the multiple needs of patients with rare diseases. The purpose of this scoping review is to examine and compare published reports on national plans, polices and legislation related to all rare diseases in different countries. We also examine strategies or programs that countries may have for these diseases. Articles were obtained from journals and books published between January 1, 2000, through December 15, 2017. Reports from the grey literature (documents issued by government and private organizations) were included if they were available on the internet. The databases used were Google and Google Scholar, PubMed, and the websites of Orphanet and the National Organization for Rare Disorders (NORD). We obtained information on 23 countries. Among these countries, the way in which rare diseases were defined varied from having similar definitions to no definition. Multinational programs supported by common or similar laws are likely to have a greater impact on rare diseases than single country programs.

A compilation of national plans, policies and government actions for rare diseases in 23 countries