Synthesis, Characterization and Antifungal Study of Five New Derivatives of E-1-(2-Hydroxyphenyl)chalcone

In an attempt to search for new and efficient antifungal agents, five chalcones namely (E)-3-(4′-diethylaminophenyl), (E)-3-(2′-ethoxyphenyl), (E)-3-(3′,4′-diethoxyphenyl), (E)-3-(2′,3′-dihydrobenzofuran-5-yl) and (E)-3-(3′,5′-bis[trifluoromethyl]phenyl)-1-(2-hydroxyphenyl) prop-2-en-1-one were synthesized from 2-hydroxyacetophenone with the corresponding substituted benzaldehydes. The synthesized chalcones were characterized by GC–MS, FTIR, 1H...