Sodium

Calcium

Endocrinology

Environmental health

Physiology

Organic chemistry

Internal medicine

Medicine

Chemistry

Disease

Journal of Hypertension

Objectives: To examine whether dietary intakes of sodium (Na) and calcium (Ca) are associated with risk of cardiovascular disease in Chinese adults. Methods: Data came from 13991 Chinese adults of the China Health and Nutrition Survey (CHNS) was analyzed. Diet was assessed by a combination of a 3-day 24-hour dietary recall and a household food inventory in each wave. Results: During a median follow up of 12.52 years, 447 adults developed cardiovascular disease with 254 men and 193 women. Compared with the lowest quintile (referent), Men in the fourth quintile of calcium intake (median: 460 mg/d, RR: 0.512, 95%CI: 0.289, 0.905), and men in the second (median: 346 mg/d, RR: 0.442, 95%CI: 0.249, 0.784) and third (median: 399 mg/d, RR: 0.553, 95%CI: 0.324, 0.945) quintile of sodium intake had lower risk for cardiovascular disease. Women in the third quintile of calcium had a decreased risk(median: 358 mg/d, RR: 0.468, 95%CI: 0.238, 0.917). However, nonsignificant trend of cardiovascular risk was found with either calcium or calcium intake (all P > 0.05). Conclusion: The results suggest that higher intake of dietary calcium and sodium didn’t have conclusive effect on the development of cardiovascular disease in Chinese population.

A18945 Dietary calcium and sodium intake and risk of cardiovascular disease in Chinese adults