Original paper
Activin E Controls Energy Homeostasis in Both Brown and White Adipose Tissues as a Hepatokine
Abstract
Brown adipocyte activation or beige adipocyte emergence in white adipose tissue (WAT) increases energy expenditure, leading to a reduction in body fat mass and improved glucose metabolism. We found that activin E functions as a hepatokine that enhances thermogenesis in response to cold exposure through beige adipocyte emergence in inguinal WAT (ingWAT). Hepatic activin E overexpression activated thermogenesis through Ucp1 upregulation in ingWAT...
Paper Details
Title
Activin E Controls Energy Homeostasis in Both Brown and White Adipose Tissues as a Hepatokine
Published Date
Oct 1, 2018
Journal
Volume
25
Issue
5
Pages
1193 - 1203
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Notes
History