Effects of mesenchymal stem cell therapy on alopecia areata in cellular and hair follicle organ culture models

Mesenchymal stem cell therapy ( MSCT ) has been suggested as a new therapeutic strategy for immunological disorders. There have been only a few attempts to treat alopecia areata ( AA ) with MSCT . MSCT efficacy and mechanism of action in treating AA are not known. We sought to investigate the effect of human hematopoietic mesenchymal stem cells ( hHMSC s) on an in vitro model of AA and to explore relevant mechanisms that regulate efficacy. An AA...