Minimum sample size for developing a multivariable prediction model: PART II - binary and time-to-event outcomes
Abstract
When designing a study to develop a new prediction model with binary or time-to-event outcomes, researchers should ensure their sample size is adequate in terms of the number of participants (n) and outcome events (E) relative to the number of predictor parameters (p) considered for inclusion. We propose that the minimum values of n and E (and subsequently the minimum number of events per predictor parameter, EPP) should be calculated to meet...
Paper Details
Title
Minimum sample size for developing a multivariable prediction model: PART II - binary and time-to-event outcomes
Published Date
Oct 24, 2018
Journal
Volume
38
Issue
7
Pages
1276 - 1296
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