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Original paper

A novel mode of capping protein-regulation by twinfilin

eLife6.40
Volume: 7
Published: Oct 23, 2018
Abstract
Cellular actin assembly is controlled at the barbed ends of actin filaments, where capping protein (CP) limits polymerization. Twinfilin is a conserved in vivo binding partner of CP, yet the significance of this interaction has remained a mystery. Here, we discover that the C-terminal tail of Twinfilin harbors a CP-interacting (CPI) motif, identifying it as a novel CPI-motif protein. Twinfilin and the CPI-motif protein CARMIL have overlapping...
Paper Details
Title
A novel mode of capping protein-regulation by twinfilin
Published Date
Oct 23, 2018
Journal
Volume
7
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